Pharmacogenomically actionable medications in a safety net health care system

Sage Open Medicine – The implementation of pharmacogenomics is increasingly relevant at the population level. Nearly 70% of Americans take at least one medication and more than 20% take five or more, with spending on medications projected to be over US$457 billion by 2019. Defined as the study of genetic variation associated with drug response, pharmacogenomics seeks to understand how genes affect the pharmacokinetics and pharmacodynamics of drugs.