Affiliate network members as force amplifiers of genomic medicine research
Future Medicine — The Implementing GeNomics In pracTicE (IGNITE) Network is an NIH-funded network dedicated to advancing the implementation of genomics in healthcare.
Pharmacogenomics competencies in pharmacy practice: A blueprint for change
Journal of the American Pharmacists Association – The emerging use of genomic data to inform medication therapy populates the medical literature and provides evidence for guidelines in the prescribing information for many medications.
Building Evidence for Clinical Use of Pharmacogenomics and Reimbursement for Testing
Advances in Molecular Pathology – In this article, the authors discuss existing data and ongoing efforts to generate evidence in support of genotype-guided therapy approaches and reimbursement for pharmacogenomic testing.
Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy
Pharmacogenetics and Genomics — Hypertension and chronic kidney disease are inextricably linked. Hypertension is a well-recognized contributor to chronic kidney disease progression and, in turn, renal disease potentiates hypertension.
Medication exposure patterns in primary care patients prescribed pharmacogenetically actionable opioids
Qualitative Report – This study’s purpose was to develop a typology of subgroups of patients who share common patterns of medication exposure. To create the typology, we used an exemplar sample of 30 patients in a large public healthcare system who had been prescribed the pharmacogenetically actionable opioids codeine or tramadol.
Physician-Reported Benefits and Barriers to Clinical Implementation of Genomic Medicine: A Multi-Site IGNITE-Network Survey
Journal of Personalized Medicine – To understand potential barriers and provider attitudes, we surveyed 285 physicians from five Implementing GeNomics In pracTicE (IGNITE) sites about their perceptions as to the clinical utility of genetic data as well as their preparedness to integrate it into practice.
Opportunities to implement a sustainable genomic medicine program: lessons learned from the IGNITE Network
Genetics in Medicine – Here we describe the findings from the National Human Genome Research Institute’s (NHGRI) Implementing GeNomics In pracTicE (IGNITE) Network in identifying key constructs, opportunities, and challenges associated with driving sustainability of genomic medicine in clinical practice.
Implementation, adoption, and utility of family health history risk assessment in diverse care settings: evaluating implementation processes and impact with an implementation framework
Genetics in Medicine – This paper describes the implementation outcomes associated with integrating a family health history–based risk assessment and clinical decision support platform within primary care clinics at four diverse healthcare systems.
Views Of Primary Care Providers On Testing Patients For Genetic Risks For Common Chronic Diseases
Health Affairs – We surveyed 488 primary care providers in community and academic practices in New York City in the period 2014–16 about their views on genetic testing for chronic diseases.
Educational strategies to enable expansion of pharmacogenomics-based care
American Journal of Health-System Pharmacy – This review summarizes requisite pharmacist competencies, educational standards, and the current state of pharmacogenomics education to propose best practice solutions for educators to meet the specific needs and challenges of this complex topic.